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Journal of Research in Ayurvedic Sciences 2022 October - December ; 6 (4) :160-168
Efficacy of Ayurveda intervention “Ayuraksha Kit” on COVID-19 incidence and outcomes: A prospective cluster randomized community-based study in India
Sunita Mata (1),  Sunita Mata (1),  Richa Singhal (1),  Richa Singhal (1),  Arunabh Tripathi (2),  Arunabh Tripathi (2),  Deepa Makhija (1),  Deepa Makhija (1),  Swati Sharma (1),  Swati Sharma (1),  Rakesh Rana (2),  Rakesh Rana (2),  Bhagwan Sahai Sharma (2),  Bhagwan Sahai Sharma (2),  Shruti Khanduri (1),  Shruti Khanduri (1),  Vinod Kumar Shahi (2),  Vinod Kumar Shahi (2),  Narayanam Srikanth (2),  Narayanam Srikanth (2),  Kishor Gavali (3),  Kishor Gavali (3),  Shashikant Vedi (4),  Shashikant Vedi (4),  Sarada Ota (5),  Sarada Ota (5),  Seema Jain (5),  Seema Jain (5),  Kuldeep Singh Kumar (6),  Kuldeep Singh Kumar (6),   Rinky Thakur (5),   Rinky Thakur (5),  Parvathy G Nair (7),  Parvathy G Nair (7),  Pratibha P Nair (7),  Pratibha P Nair (7),  PS Aswani (7),  PS Aswani (7),  Susmita Priyadarshinee Otta (8),  Susmita Priyadarshinee Otta (8),  Kshirod Kumar Ratha (8),  Kshirod Kumar Ratha (8),  Dipsunder Sahu (9),  Dipsunder Sahu (9),   Debajyoti Das (9),   Debajyoti Das (9),  Harbans Singh (10),  Harbans Singh (10),  Avvaru Jai Venkata Sai Prasad (11),  Avvaru Jai Venkata Sai Prasad (11),  Sangeeta Sangvikar (10),  Sangeeta Sangvikar (10),  Alok Kumar Shrivastava (12),  Alok Kumar Shrivastava (12),  Pallavi Namdev Kamble (12),  Pallavi Namdev Kamble (12),  Laxman Bhurke (13),  Laxman Bhurke (13),  Govind Reddy (13),  Govind Reddy (13),  Saylee Hemant Deshmukh (14),  Saylee Hemant Deshmukh (14),  Deepa Sharma (15),  Deepa Sharma (15),  Neelam Kumari Singh (16),  Neelam Kumari Singh (16),  Savita Poshatti Gopod (17),  Savita Poshatti Gopod (17),  Chagamreddy Murali Krishna (17),  Chagamreddy Murali Krishna (17),  Vanmala Wakode (18),  Vanmala Wakode (18),  Emy S Surendram (19),  Emy S Surendram (19),  TP Sinimol (19),  TP Sinimol (19),  Vimal Tewari (20),  Vimal Tewari (20),  PL Bharti (21),  PL Bharti (21),  Girindra Kumar Bora (21),  Girindra Kumar Bora (21),  Shri Prakash (22),  Shri Prakash (22),  Rahul Dhanraji Ghuse (22),  Rahul Dhanraji Ghuse (22),  Gopesh Kumar (23),  Gopesh Kumar (23),  Poonam Mohod (24),  Poonam Mohod (24),  Vineeta Negi (25),  Vineeta Negi (25),  Chris Antony (25),  Chris Antony (25),  Sumed Narayanrao Paikrao (26),  Sumed Narayanrao Paikrao (26),  Anil Avhad (26),  Anil Avhad (26),  MN Shubhashree (27),  MN Shubhashree (27),  Raghavendra Naik (27),  Raghavendra Naik (27),  S Asha (28),  S Asha (28)  

Abstract
BACKGROUND: Ayurvedic medicines have been used as preventative care and for managing COVID-19 in India from the early days of the pandemic. This study was conducted to evaluate the effectiveness of the Ayuraksha kit (ARK), a combination of four extensively used Ayurvedic interventions, as prophylactic care against COVID-19. OBJECTIVE: The primary objective was to observe the non-occurrence of COVID-19, and the secondary objective was to observe the changes in the general well-being and manifestation of COVID-19-like symptoms in the participants. MATERIAL AND METHODS: This was a prospective, open-label, multi-center, cluster randomized community-based study conducted from October 2020-March 2021 in India. A total of 153047 participants of either sex, aged 18 - 70 years, living in Scheduled Caste dominated areas of 18 identified states in India, were enrolled. The clusters from where at least one COVID-19 case was identified were randomized and allocated into two groups. In Group-I (n = 1,34,364), Ayuraksha Kit, which contains (Chyawanprash 6 gm once daily; Ayush Kwatha 75?ml once daily; Samshamani Vati 500?mg twice daily and Anu Taila one drop in each nostril twice daily) was administered for one month along with the standard preventive measures for COVID-19. In Group II (n = 18,683), only standard preventive measures for COVID-19 as per the existing guidelines were followed. RESULT: The proportion of participants who did not report having COVID-19 were significantly higher (98.9%)in the ARK group than in the control group (98.1%) after adjusting the history of contact with COVID-19 positive subject/contact with a person having COVID-19 symptoms. The proportion of participants with COVID-19 symptoms was slightly more in the control group. Among the COVID-19-positive cases, symptomatic cases were more in the ARK group, but the incidence of hospitalization (9.8%) was much lesser than that of the control group (12.5%). Improvements in general well-being (appetite, bowel, and sleep quality) were better in the ARK group than in the control group. The medicines in the ARK were well tolerated. CONCLUSIONS: ARK may be used for general well-being and as prophylaxis for preventing COVID-19 infection. Keywords: Anu taila, Ayurveda, Ayush Kwath, Chyawanprash, COVID-19, Samshamani Vati

DHARA ID: D060682


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